Commercial Property for Sale In North East Florida Jacksonville - Orange Park - St Augustine - Middleburg - Beaches

šŸ¢ Commercial Property For Sale In Northeast Florida

Grow your business or expand your investment portfolio in one of Floridaā€™s fastest-growing regions.

If youā€™re searching for commercial real estate in Northeast Florida, youā€™re in the right place. Whether you need retail space, office buildings, warehouses, or land for future development, Northeast Florida offers a wide range of opportunities for both investors and business owners.

From the bustling corridors of Jacksonville to the emerging growth areas of Clay County, St. Johns County, and Bradford County, this region combines a strong economy, expanding population, and business-friendly environment ā€” making it one of Floridaā€™s top destinations for commercial investment. See more details below.

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106 ST. GEORGE STREET, St. Augustine, Florida 32084 MLS 2087504

106 ST. GEORGE STREET, St. Augustine, Florida 32084

1Picture(s)
600Sqft
Don't miss your chance to own not one, but two profitable and well-established retail businesses in the heart of historic downtown St. Augustine. Both retail spaces are ideally positioned along the highly trafficked and pedestrian-only St. George Street, ensuring visibility and foot traffic year-round. This turnkey package deal includes: One retail space approx.
$125,000

345 COUNTY ROAD 315, Interlachen, Florida 32148 MLS 2113107

345 COUNTY ROAD 315, Interlachen, Florida 32148

3Picture(s)
0Sqft
COMMERCIAL PROPERTY LOCATED IN PUTNAM COUNTY – Are you ready to build your Commercial dreams? We have the perfect acreage for you. This property has State Road frontage in INTERLACHEN – 1.26 acres on South Hwy 315. Zoned Commercial with adjacent property for sale. Within Putnam County (lower taxes).
$120,000

17 43RD, Jacksonville, Florida 32208 MLS 2108747

17 43RD, Jacksonville, Florida 32208

31Picture(s)
1,000Sqft
*** Smoke Shop business only available for sale Located next to a newly remodeled and very busy laundromat. Flexible Lease term with only $1500 a month (not a NNN lease) Great opportunity for owner operator to start their own business…. the business currently run by a full time employees….
$120,000

0 SOUTEL, Jacksonville, Florida 32219 MLS 2064770

0 SOUTEL, Jacksonville, Florida 32219

8Picture(s)
0.25Sqft
Location, Location , Location !!!!!!!! if you are looking for perfect location for your business , that is what you are looking for. intersection and shopping area is perfect for your business. Imagine the potential for this high visibility location .Take advantage of the prime location and book a viewing today to elevate your business.
$120,000

5506 AVENUE B, Jacksonville, Florida 32209 MLS 2115500

5506 AVENUE B, Jacksonville, Florida 32209

41Picture(s)
3,228Sqft
OPTIONS, OPTIONS, OPTIONS. INVESTORS, this building have many options, located on Residential/commercial area can be used either way, with great space for parking outside, with 2 offices sapce on the first floor and an apartment on the second floor that can be used as office space too. THIS WONT LAST….
$119,500

1428 ST JOHNS, Palatka, Florida 32177 MLS 2086768

1428 ST JOHNS, Palatka, Florida 32177

4Picture(s)
1,280Sqft
Incredible opportunity in the heart of Palatka. The local radio station is on the move so the building and lot are now available. 1280sqft, heated and cooled zoned C-2, high traffic, perfect for an office, retail, etc. Building was originally setup as a home but the kitchen was removed. Full bath and half bath still intact with 4 office areas and a lobby.
$115,000

2550 STATE, Bunnell, Florida 32110 MLS 2068085

2550 STATE, Bunnell, Florida 32110

21Picture(s)
1,000Sqft
Turnkey physical therapy business for sale with assumable lease. Landlord agreeable to executing a long-term lease with a qualified buyer. Facility is 1000 SF and features reception area, waiting area, office, restroom, and three treatment rooms. HVAC system was replaced in 2019. Established client base with both insured and private-pay clients.
$110,000

341 COUNTY ROAD 315, Interlachen, Florida 32148 MLS 2113431

341 COUNTY ROAD 315, Interlachen, Florida 32148

6Picture(s)
0Sqft
COMMERCIAL PROPERTY LOCATED IN PUTNAM COUNTY – Are you ready to build your Commercial dreams? We have the perfect acreage for you. This property features state road frontage in Interlachen, with 0.77 acres on South Hwy 315. Zoned Commercial with adjacent property for sale. Within Putnam County (lower taxes).
$100,000

541 TALLEYRAND, Jacksonville, Florida 32202 MLS 2103364

541 TALLEYRAND, Jacksonville, Florida 32202

3Picture(s)
1,336Sqft
Here is your opportunity to own a turnkey business near downtown Jacksonville. The business has all items needed to run a restaurant and convenience store.
$100,000

1310 ST JOHNS, Palatka, Florida 32177 MLS 2118231

1310 ST JOHNS, Palatka, Florida 32177

12Picture(s)
934Sqft
Fantastic commercial opportunity in the City of Palatka! This 932 sq ft property is zoned C-2, offering excellent flexibility for a wide range of business uses. The interior has already been fully gutted, providing a clean slate that's ready for your custom build-out and vision.
$64,900

1545 COUNTY ROAD 220, Fleming Island, Florida 32003 MLS 2112410

1545 COUNTY ROAD 220, Fleming Island, Florida 32003

5Picture(s)
73,652Sqft
Well established Beauty Salon business only available for sale. located in a very busy Shopping center with many successful retail stores. *** Great opportunity for owner operator to aquire this business with potential to add many other services in the Beauty industry.
$60,000

224 HIGHWAY 17, Palatka, Florida 32177 MLS 2073772

224 HIGHWAY 17, Palatka, Florida 32177

9Picture(s)
0Sqft
Excellent Commercial Development Opportunity in Palatka! Two prime parcels, totaling approximately 0.39 acres, are now available in a highly desirable commercial location. Zoned C-2, this corner lot boasts exceptional visibility and exposure, with an impressive average annual daily traffic count (AADT) of 9,100 vehicles.
$59,900
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šŸŒ“ Why Invest in Northeast Florida Commercial Real Estate

1. Strategic Location & Infrastructure
Northeast Florida sits at the crossroads of I-95, I-10, and major ports, making it ideal for logistics, retail, and industrial operations. Businesses benefit from proximity to Jacksonville International Airport, JAXPORT, and rail connections.

2. Population & Economic Growth
With rapid expansion in communities like Nocatee, Middleburg, Lake Asbury, and Green Cove Springs, local demand for retail, office, and service-based properties continues to climb.

3. Affordable Entry Point
Compared to South Florida and Central Florida markets, commercial land and buildings in Northeast Florida remain competitively priced, giving investors stronger ROI potential.

4. Diverse Property Types
Find everything from turnkey office complexes and retail plazas to vacant commercial land ready for development.

šŸ” Search Commercial Properties for Sale in Northeast Florida

Use the interactive MLS search tool above to browse current commercial listings across Jacksonville, Orange Park, Green Cove Springs, Lake Asbury, Starke, Ponte Vedra, and surrounding areas.

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šŸ’¼ Work with a Local Commercial Real Estate Expert

Mike Schwiebert, REALTORĀ® | 904HomeStore.com

As a licensed REALTORĀ®, former builder, and North Florida resident, Mike brings a unique perspective to commercial real estate. He understands zoning, site development, and investment analysis ā€” helping you make informed decisions and negotiate the best deal.

Whether youā€™re:

  • Buying land to build a new facility

  • Selling an existing business property

  • Expanding your investment portfolio

ā€¦Mike provides local expertise and a hands-on approach that helps clients get more value in every transaction.

šŸ“ Serving Jacksonville, Clay County, St. Johns County, Bradford County, and all of Northeast Florida.
šŸ“ž Call or text Mike SchwiebertĀ for a personalized consultation.

Mike

See Come Vacant Lots ā€“ land for sale hereĀ HERE
If you are looking to buy or sell a home on Black Creek you have come to the right place. I would love to help you find your next home. When you see something you like please call, text, or email me anytime and I will get to work for you. Call Mike Schwiebert Realtor at 904-562-9345. VotedĀ Best Real Estate Agent 2019 in Clay County!

Mike Schwiebert Best Realtor In Clay County