🏢 Commercial Property For Sale In Northeast Florida

Grow your business or expand your investment portfolio in one of Florida’s fastest-growing regions.

If you’re searching for commercial real estate in Northeast Florida, you’re in the right place. Whether you need retail space, office buildings, warehouses, or land for future development, Northeast Florida offers a wide range of opportunities for both investors and business owners.

From the bustling corridors of Jacksonville to the emerging growth areas of Clay County, St. Johns County, and Bradford County, this region combines a strong economy, expanding population, and business-friendly environment — making it one of Florida’s top destinations for commercial investment. See more details below.

 

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1201 CASSAT, Jacksonville, Florida 32205 MLS 2128328

1201 CASSAT, Jacksonville, Florida 32205

37Picture(s)

1,375Sqft

Unlock the potential of Murray Hill with this prime corner opportunity located on a high-visibility lot along Cassat Avenue. This freestanding building places your business directly in front of so many vehicles every single day, guaranteeing exceptional brand exposure. The 1375 square foot space sits on a 0.

$215,000

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3226 PEARL, Jacksonville, Florida 32206 MLS 2129523

3226 PEARL, Jacksonville, Florida 32206

11Picture(s)

356Sqft

Attention investors! Don't miss this value-add opportunity in one of Jacksonville's rapidly developing areas. Situated on a spacious 0.21-acre lot, Small Commercial Office Building and double wide Lot. Space is currently being use as a barbershop and Hand Carwash. Large lot provides flexibility for improvements, expansion, or long-term appreciation play.

$214,999

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3108 MYRTLE, Jacksonville, Florida 32209 MLS 2120040

3108 MYRTLE, Jacksonville, Florida 32209

7Picture(s)

1,392Sqft

Income-producing and full of potential! This active rooming house offers steady cash flow with 1,392 sq ft of flexible space in a growing commercial corridor.

$200,000

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3104 MYRTLE, Jacksonville, Florida 32209 MLS 2120038

3104 MYRTLE, Jacksonville, Florida 32209

4Picture(s)

2,450Sqft

Endless potential in this high-visibility commercial property on Myrtle Ave! With 2,450 sq ft of solid 1930 masonry construction, this building is a perfect canvas for a retail shop, boutique studio, office space, café, wellness center, or creative business after renovation.

$200,000

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325 MERRITT ISLAND, Merritt Island, Florida 32952 MLS 2118302

325 MERRITT ISLAND, Merritt Island, Florida 32952

14Picture(s)

1,600Sqft

Open house Saturday 11/29. Creative financing available, motivated. Turnkey and well-established pizzeria & Italian restaurant located on high-traffic SR 520 in Merritt Island. Mimmo's Pizza & Italian Kitchen is a local favorite with strong financials, steady growth, and a loyal customer base. Prime plaza location with excellent visibility and ample parking.

$200,000

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2905 MONCRIEF, Jacksonville, Florida 32209 MLS 2092399

2905 MONCRIEF, Jacksonville, Florida 32209

8Picture(s)

1,932Sqft

Property Highlights: Unlock the potential of this versatile 1,932 sq ft mixed-use building ideally situated on a high-visibility main road with strong frontage and prominent signage opportunities. Zoned RMD-A, this property offers a wide range of potential uses—from retail, professional offices, salon, boutique, or studio, to residential or short-term rental upstairs.

$200,000

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4505 ST JOHNS, Palatka, Florida 32177 MLS 2012398

4505 ST JOHNS, Palatka, Florida 32177

9Picture(s)

0Sqft

Build your business on this partially cleared acreage with approximately 230 ft of frontage on heavily traveled St. Johns Ave. Over 4+ total acres that includes a pond. Sidewalk in front of property. Property is close to St. Johns River State College and State Rd 19. Motivated Seller – Will Consider All Offers.

$199,900

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4171 COUNTY ROAD 218, Middleburg, Florida 32068 MLS 1245415

4171 COUNTY ROAD 218, Middleburg, Florida 32068

6Picture(s)

0Sqft

One of three lots near Blanding Interchange Fast growing area with Large Anchor stores and Restaurants. Many single family homes in the area to support any commercial endeavor. Broad Zoning to accommodate many commercial uses. Road being widened now to accommodate expanding traffic count in this rapidly growing area.

$199,900

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4189 COUNTY ROAD 218, Middleburg, Florida 32068 MLS 1245405

4189 COUNTY ROAD 218, Middleburg, Florida 32068

6Picture(s)

0Sqft

One of three lots near Blanding Interchange Fast growing area with Large Anchor stores and Restaurants. Many single family homes in the area to support any commercial endeavor. Broad Zoning to accommodate many commercial uses. Road being widened now to accommodate expanding traffic count in this rapidly growing area.

$199,900

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4183 COUNTY ROAD 218, Middleburg, Florida 32068 MLS 1245110

4183 COUNTY ROAD 218, Middleburg, Florida 32068

6Picture(s)

0Sqft

One of three lots near Blanding Interchange Fast growing area with Large Anchor stores and Restaurants. Many single-family homes in the area to support any commercial endeavor. Broad Zoning to accommodate many commercial uses Road being widened now to accommodate expanding traffic count in this rapidly growing area.

$199,900

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921 MOODY, Palatka, Florida 32177 MLS 2136389

921 MOODY, Palatka, Florida 32177

2Picture(s)

0Sqft

2.22 Acres Zoned C-1 – Prime Commercial Opportunity in Growing Area Rare opportunity to own 2.22 acres of commercially zoned (C-1) property in a rapidly expanding area. This parcel is ideally positioned directly in front of a newly developed townhome community, offering excellent exposure to a growing residential population.

$189,000

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228 YELVINGTON, East Palatka, Florida 32131 MLS 2119521

228 YELVINGTON, East Palatka, Florida 32131

32Picture(s)

1,740Sqft

ENDLESS POSSIBILITIES! RURAL CHURCH ON CORNER LOT-READY FOR RESTORATION OR CREATIVE CONVERSION. Discover the charm and potential of this former country church situated on an AG zoned .61 acre corner lot in a quiet rural setting.

$185,000

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🌴 Why Invest in Northeast Florida Commercial Real Estate

1. Strategic Location & Infrastructure
Northeast Florida sits at the crossroads of I-95, I-10, and major ports, making it ideal for logistics, retail, and industrial operations. Businesses benefit from proximity to Jacksonville International Airport, JAXPORT, and rail connections.

2. Population & Economic Growth
With rapid expansion in communities like Nocatee, Middleburg, Lake Asbury, and Green Cove Springs, local demand for retail, office, and service-based properties continues to climb.

3. Affordable Entry Point
Compared to South Florida and Central Florida markets, commercial land and buildings in Northeast Florida remain competitively priced, giving investors stronger ROI potential.

4. Diverse Property Types
Find everything from turnkey office complexes and retail plazas to vacant commercial land ready for development.

🔍 Search Commercial Properties for Sale in Northeast Florida

Use the interactive MLS search tool above to browse current commercial listings across Jacksonville, Orange Park, Green Cove Springs, Lake Asbury, Starke, Ponte Vedra, and surrounding areas.

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• Property Type (Retail, Office, Industrial, Land, Multi-Use)

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💼 Work with a Local Commercial Real Estate Expert

Mike Schwiebert, REALTOR® | 904HomeStore.com

As a licensed REALTOR®, former builder, and North Florida resident, Mike brings a unique perspective to commercial real estate. He understands zoning, site development, and investment analysis — helping you make informed decisions and negotiate the best deal.

Whether you’re:

• Buying land to build a new facility

• Selling an existing business property

• Expanding your investment portfolio

…Mike provides local expertise and a hands-on approach that helps clients get more value in every transaction.

📍 Serving Jacksonville, Clay County, St. Johns County, Bradford County, and all of Northeast Florida.
📞 Call or text Mike Schwiebert for a personalized consultation.