🏢 Commercial Property For Sale In Northeast Florida

Grow your business or expand your investment portfolio in one of Florida’s fastest-growing regions.

If you’re searching for commercial real estate in Northeast Florida, you’re in the right place. Whether you need retail space, office buildings, warehouses, or land for future development, Northeast Florida offers a wide range of opportunities for both investors and business owners.

From the bustling corridors of Jacksonville to the emerging growth areas of Clay County, St. Johns County, and Bradford County, this region combines a strong economy, expanding population, and business-friendly environment — making it one of Florida’s top destinations for commercial investment. See more details below.

 

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6974 MOUNT VERNON, Glen St. Mary, Florida 32040 MLS 2116221

6974 MOUNT VERNON, Glen St. Mary, Florida 32040

3Picture(s)

1,991Sqft

This commercial corner lot of approximately .62 +/- acres is located in the heart of Glen St. Mary, FL. The CG zoning allows for most retail uses including restaurants, shopping centers, and service establishments. There is approximately 140 ft of frontage on Hwy 90. The traffic count is about 10,900 AADT. This property was formally an auto repair facility.

$299,900

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3840 WILLAIMSBURG PARK, Jacksonville, Florida 32257 MLS 2116754

3840 WILLAIMSBURG PARK, Jacksonville, Florida 32257

11Picture(s)

1,430Sqft

REDUCED. This Mandarin office condo is move-in ready with new flooring throughout. The space is ideal for any professional or medical use and consists of a reception area, four (4) private offices, a kitchen/break room, and a restroom. This corner unit offers an abundance of sunlight and is tucked into the back of a quiet office park. The roof of the building was completed this year (2025).

$299,000

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7069 CRILL, Palatka, Florida 32177 MLS 788470

7069 CRILL, Palatka, Florida 32177

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0Sqft

2+ acre double corner lot, zoned C-1. Property has approximately 390 ft of road frontage on heavily traveled Crill Ave for great exposure. Located in the county. Sellers are extremely motivated & will consider all offers.

$299,000

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4164 COUNTY ROAD 218, Middleburg, Florida 32068 MLS 2007220

4164 COUNTY ROAD 218, Middleburg, Florida 32068

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0Sqft

Here is your chance to own commercial property in the up and coming town of Middleburg. This property is mostly cleared and close to everything that Middleburg has to offer. Located next to a National Franchise Domino's Pizza with hign traffic. Zoning information listed under document tab BB. Water and Sewer lines are already established along property easement along 218.

$295,000

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1308 UNIVERSITY, Jacksonville, Florida 32211 MLS 2036487

1308 UNIVERSITY, Jacksonville, Florida 32211

1Picture(s)

2,328Sqft

SELLER HAS 10 MORE RESIDENTIAL AND COMMERCIAL PROPERTIES IN ARLINGTON AND SOUTHSIDE AREA. MLS NUMBERS: #2036487;#2084056:#2085540;# 2082320:#2085631:#2061514:#2085627:#1233574:# 2085629SELLER FINANCE AVAILABLE WITH THE BEST TERMS AND ITS OPTIONAL FOR THE BUYER.

$291,600

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00 COMMERCIAL, Keystone Heights, Florida 32656 MLS 2108669

00 COMMERCIAL, Keystone Heights, Florida 32656

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0Sqft

One of the last few Vacant Land Commercial Properties left in the City Limits of Keystone Heights. Nicely Wooded lot consisting of 1.12 Acres High & Dry. 440 Feet Frontage on the Curved Paved Road on Commercial Circle.

$289,000

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0 CONFIDENTIAL, Fernandina Beach, Florida 32034 MLS 2117085

0 CONFIDENTIAL, Fernandina Beach, Florida 32034

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0Sqft

** Business Sale Only** Exceptional investment opportunity! Two well-established and reputable Quick Change Oil & Lube service centers located in Fernandina Beach, FL and St. Marys, GA. Both locations boast strong local recognition, loyal repeat clientele, and consistent performance over the years.

$280,000

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101 PIONEER, Palatka, Florida 32177 MLS 2099125

101 PIONEER, Palatka, Florida 32177

51Picture(s)

1,512Sqft

This unique property offers exceptional flexibility, having been previously utilized as a residence and ideally suited to continue serving either residential or commercial needs. Perfectly positioned directly across the street from the hospital, it presents a rare opportunity for live/work use or a professional office in a high-demand area.

$279,900

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13453 MAIN, Jacksonville, Florida 32218 MLS 2097524

13453 MAIN, Jacksonville, Florida 32218

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1,250Sqft

Prime Commercial Office Condo Investment Opportunity located on prestigious North Main Street—a professional office condo that combines investment potential and stability. With a competitive 7% cap rate and fully occupied until 2029 with rent increases annually, this property presents an attractive proposition for discerning investors seeking solid returns.

$278,000

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2919 PHILIPS, Jacksonville, Florida 32207 MLS 2088625

2919 PHILIPS, Jacksonville, Florida 32207

1Picture(s)

1,403Sqft

C

$275,000

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736 S HIGHWAY 17, San Mateo, Florida 32187 MLS 2084445

736 S HIGHWAY 17, San Mateo, Florida 32187

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0Sqft

Prime Commercial Opportunity in a Growing Area – Unlock the value of 1.54 acres of C-2 zoned property located in a rapidly developing area. Currently operating as a flea market with 34 individual stands/buildings, this versatile site offers a unique opportunity for both investors and developers. Continue to run the existing flea market or reimagine the entire space to suit your vision.

$270,800

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323 MARTIN LUTHER KING, Macclenny, Florida 32063 MLS 2121476

323 MARTIN LUTHER KING, Macclenny, Florida 32063

28Picture(s)

2,223Sqft

We all need something or someone to believe in. The best place to start could be at 323 M L King. It is never too late for new beginnings. Have you ever needed an upgrade or just to downsize? The owners have a facility that they would like to offer for a New Improved Price. A beautifully furnished Church. When making a purchase one of the first questions asked is what and when was it replaced.

$270,000

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🌴 Why Invest in Northeast Florida Commercial Real Estate

1. Strategic Location & Infrastructure
Northeast Florida sits at the crossroads of I-95, I-10, and major ports, making it ideal for logistics, retail, and industrial operations. Businesses benefit from proximity to Jacksonville International Airport, JAXPORT, and rail connections.

2. Population & Economic Growth
With rapid expansion in communities like Nocatee, Middleburg, Lake Asbury, and Green Cove Springs, local demand for retail, office, and service-based properties continues to climb.

3. Affordable Entry Point
Compared to South Florida and Central Florida markets, commercial land and buildings in Northeast Florida remain competitively priced, giving investors stronger ROI potential.

4. Diverse Property Types
Find everything from turnkey office complexes and retail plazas to vacant commercial land ready for development.

🔍 Search Commercial Properties for Sale in Northeast Florida

Use the interactive MLS search tool above to browse current commercial listings across Jacksonville, Orange Park, Green Cove Springs, Lake Asbury, Starke, Ponte Vedra, and surrounding areas.

Filter by:

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💼 Work with a Local Commercial Real Estate Expert

Mike Schwiebert, REALTOR® | 904HomeStore.com

As a licensed REALTOR®, former builder, and North Florida resident, Mike brings a unique perspective to commercial real estate. He understands zoning, site development, and investment analysis — helping you make informed decisions and negotiate the best deal.

Whether you’re:

• Buying land to build a new facility

• Selling an existing business property

• Expanding your investment portfolio

…Mike provides local expertise and a hands-on approach that helps clients get more value in every transaction.

📍 Serving Jacksonville, Clay County, St. Johns County, Bradford County, and all of Northeast Florida.
📞 Call or text Mike Schwiebert for a personalized consultation.