🏢 Commercial Property For Sale In Northeast Florida

Grow your business or expand your investment portfolio in one of Florida’s fastest-growing regions.

If you’re searching for commercial real estate in Northeast Florida, you’re in the right place. Whether you need retail space, office buildings, warehouses, or land for future development, Northeast Florida offers a wide range of opportunities for both investors and business owners.

From the bustling corridors of Jacksonville to the emerging growth areas of Clay County, St. Johns County, and Bradford County, this region combines a strong economy, expanding population, and business-friendly environment — making it one of Florida’s top destinations for commercial investment. See more details below.

 

All

For sale

For Rent

Sort by:

• Price Descending
• Newest
• Bedrooms
• Featured

Price DescendingPrice AscendingNewestOldestBedrooms descendingBedrooms ascendingFeatured descendingFeatured ascending

Grid

List

Map

Save Search

More Details

6126 ATLANTIC, Jacksonville, Florida 32211 MLS 2136143

6126 ATLANTIC, Jacksonville, Florida 32211

13Picture(s)

2,965Sqft

Welcome to your next business headquarters- zoned CRO- the possibilities are ENDLESS (well almost)! This freshly renovated commercial building, nestled on a generous 0.67-acre lot, is a testament to modernity and functionality. Boasting prime road frontage, this property is not just a space; it's a statement.

$862,654

More Details

554 MARKET, St. Augustine, Florida 32095 MLS 2106657

554 MARKET, St. Augustine, Florida 32095

89Picture(s)

3,916Sqft

Palencia in St. Johns County in St. Augustine is an upscale community that attracts great tenants. Currently a 7 Cap. If managed well, at current pace then one should be able to project 3-4% yearly increase in revenue and long-term leases are positioned as such. Short-term rental option for one of three units.

$859,000

More Details

715 MCDUFF, Jacksonville, Florida 32209 MLS 2122457

715 MCDUFF, Jacksonville, Florida 32209

183Picture(s)

9,450Sqft

Prime commercial site on 0.21 acres at the major intersection of McDuff Ave & Beaver St with high visibility, easy access, & steady traffic flow just minutes from Downtown Jacksonville. Zoned CCG-2 for broad commercial uses (retail, restaurants-incl.

$850,000

More Details

145 HILDEN, Ponte Vedra, Florida 32081 MLS 2121967

145 HILDEN, Ponte Vedra, Florida 32081

10Picture(s)

0Sqft

Joni's Pizza, a beloved, family-owned Italian restaurant with 17 years of successful operation, is now offered for sale including both the business and the condo.

$850,000

More Details

30 BARBER, Macclenny, Florida 32063 MLS 2108115

30 BARBER, Macclenny, Florida 32063

43Picture(s)

6,544Sqft

Available now: SELLER FINANCING AVAILABLE for this 6,544 sq ft industrial warehouse in a prime Macclenny, FL location just off the main road. Zoned for industrial use, this versatile space features 3-phase power, two HVAC units, and an open-air floor plan ideal for manufacturing, distribution, or storage.

$850,000

More Details

2706 OLD MOULTRIE, St. Augustine, Florida 32086 MLS 2104450

2706 OLD MOULTRIE, St. Augustine, Florida 32086

18Picture(s)

2,276Sqft

A great opportunity with multiple uses to include medical office, professional office, veterinary office, day care, senior care, retail, churches, restaurant or even your own personal compound with tremendous upside! The existing 2,276 SF standalone building is in excellence condition and ready to take on any business or family for that matter. You have 2.18 Acres of Uplands on the 3.

$850,000

More Details

751 HIGHWAY 17, San Mateo, Florida 32187 MLS 2088629

751 HIGHWAY 17, San Mateo, Florida 32187

24Picture(s)

672Sqft

Strategically positioned at the high-traffic intersection of US Highway 17 and Horse Landing Road, this Commercial/R-2 property presents a compelling opportunity for developers and investors alike.

$850,000

More Details

0 LUNDY, Palatka, Florida 32177 MLS 2099903

0 LUNDY, Palatka, Florida 32177

6Picture(s)

0Sqft

Rare Opportunity! This is the only privately owned multi acre parcel around the Palatka Golf Club, which was designed by Donald Ross in 1925. Two parcels for a total of 15.73 +/- acres, with frontage on the 11th, 12th, and 14th greens. This property has a very unique terrain and is currently zoned R-1AA. Great potential for development of multi-family with rezoning.

$847,000

More Details

167 COMFORT, Palatka, Florida 32177 MLS 2084258

167 COMFORT, Palatka, Florida 32177

29Picture(s)

9,050Sqft

Exceptional Commercial/Flex Space Opportunity in Palatka's Growing Port District Unlock the potential for your business with this expansive 9,050 sq. ft. commercial/flex space situated on a substantial 3.19-acre lot.

$845,000

More Details

7638 MAILES, Jacksonville, Florida 32210 MLS 2136765

7638 MAILES, Jacksonville, Florida 32210

19Picture(s)

4,104Sqft

Turnkey investment opportunity in a rapidly growing Jacksonville market. 7368 Mailes Ct is a newly constructed (2023) four-unit multifamily property, each offering 2 bedrooms and 2 bathrooms with modern finishes and strong rental appeal. Three units are currently leased, providing immediate income with upside through lease-up of the final unit.

$825,000

More Details

7749 NORMANDY, Jacksonville, Florida 32221 MLS 2119271

7749 NORMANDY, Jacksonville, Florida 32221

4Picture(s)

2,400Sqft

For Sale: Established Liquor Store business plus 3PS License. Turnkey opportunity to own an established liquor store with a drive through window in a high-traffic area. This business has a loyal customer base and consistent sales. The store features a diverse inventory, including popular wines, spirits and specialty items.

$800,000

More Details

MLS 2129939

12Picture(s)

4,814Sqft

Prime daycare facility Including property and business for sale in the busy and ever growing Orange Park Fl, licensed for up to 133 children and currently operating with 35 enrolled students. This income-producing childcare center offers significant upside potential for expansion.

$799,900

• Previous
• 1
• 2
• …
• 11
• 12
• 13
• …
• 28
• 29
• Next

343 Results returned.Per Page 612182430100

🌴 Why Invest in Northeast Florida Commercial Real Estate

1. Strategic Location & Infrastructure
Northeast Florida sits at the crossroads of I-95, I-10, and major ports, making it ideal for logistics, retail, and industrial operations. Businesses benefit from proximity to Jacksonville International Airport, JAXPORT, and rail connections.

2. Population & Economic Growth
With rapid expansion in communities like Nocatee, Middleburg, Lake Asbury, and Green Cove Springs, local demand for retail, office, and service-based properties continues to climb.

3. Affordable Entry Point
Compared to South Florida and Central Florida markets, commercial land and buildings in Northeast Florida remain competitively priced, giving investors stronger ROI potential.

4. Diverse Property Types
Find everything from turnkey office complexes and retail plazas to vacant commercial land ready for development.

🔍 Search Commercial Properties for Sale in Northeast Florida

Use the interactive MLS search tool above to browse current commercial listings across Jacksonville, Orange Park, Green Cove Springs, Lake Asbury, Starke, Ponte Vedra, and surrounding areas.

Filter by:

• Property Type (Retail, Office, Industrial, Land, Multi-Use)

• Price Range

• Square Footage

• City or County

💼 Work with a Local Commercial Real Estate Expert

Mike Schwiebert, REALTOR® | 904HomeStore.com

As a licensed REALTOR®, former builder, and North Florida resident, Mike brings a unique perspective to commercial real estate. He understands zoning, site development, and investment analysis — helping you make informed decisions and negotiate the best deal.

Whether you’re:

• Buying land to build a new facility

• Selling an existing business property

• Expanding your investment portfolio

…Mike provides local expertise and a hands-on approach that helps clients get more value in every transaction.

📍 Serving Jacksonville, Clay County, St. Johns County, Bradford County, and all of Northeast Florida.
📞 Call or text Mike Schwiebert for a personalized consultation.