🏢 Commercial Property For Sale In Northeast Florida

Grow your business or expand your investment portfolio in one of Florida’s fastest-growing regions.

If you’re searching for commercial real estate in Northeast Florida, you’re in the right place. Whether you need retail space, office buildings, warehouses, or land for future development, Northeast Florida offers a wide range of opportunities for both investors and business owners.

From the bustling corridors of Jacksonville to the emerging growth areas of Clay County, St. Johns County, and Bradford County, this region combines a strong economy, expanding population, and business-friendly environment — making it one of Florida’s top destinations for commercial investment. See more details below.

 

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1851 UNIVERSITY, Jacksonville, Florida 32216 MLS 2116765

1851 UNIVERSITY, Jacksonville, Florida 32216

19Picture(s)

2,140Sqft

Freestanding office building offering 2,140 +/- SF with an abundance of parking behind the building. There are three (3) private offices, two (2) restrooms, one (1) kitchen and spacious ''bullpen'' areas for cubicles or an open office design concept. Excellent exposure along University Blvd. Estimated NNN to be $3.30 p.s.f.

$2,853

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2140 KINGSLEY, Orange Park, Florida 32073 MLS 2118461

2140 KINGSLEY, Orange Park, Florida 32073

49Picture(s)

1,444Sqft

Prime medical office opportunity in an unbeatable location. Situated in the Medical Arts Center of Orange Park, this updated office is just a short walk from HCA Florida Orange Park Hospital, making it ideal for medical professionals seeking convenience and visibility. The interior features fresh paint, updated baseboards, and modern hardware throughout.

$2,850

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135 LAND GRANT, St. Augustine, Florida 32092 MLS 2121922

135 LAND GRANT, St. Augustine, Florida 32092

24Picture(s)

1,102Sqft

Medical / Professional Office Condo for Lease located at 135 Land Grant Street, Suite 2, St. Augustine, FL in the World Golf Village Professional Center. This brand new office suite features reception and 5 large private offices is ideal for medical, executive office, law firm, CPA, or other professional users seeking a prestigious St. Johns County business address.

$2,800

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8802 CORPORATE SQUARE, Jacksonville, Florida 32216 MLS 2110299

8802 CORPORATE SQUARE, Jacksonville, Florida 32216

12Picture(s)

29,680Sqft

8802 Corporate Square Court is located in Jacksonville's Southside sub-market, positioned in a well-regarded industrial/business park just off I-295. The property spans roughly 29,680 SF across four flexible buildings, with spaces available in the 920 +/- SF – 1,840 +/- SF range.

$2,760

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1873 EVERLEE, Jacksonville, Florida 32216 MLS 2116716

1873 EVERLEE, Jacksonville, Florida 32216

29Picture(s)

1,542Sqft

Excellent opportunity to lease a well-located industrial/flex building just minutes from I-95, I-295, and the Jacksonville International Airport. The property offers outstanding functionality for a wide range of users — including light manufacturing, service contractors, storage, or distribution operations. The building features an open layout adaptable for office or mixed-use needs.

$2,699

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145 LAND GRANT, St. Augustine, Florida 32092 MLS 2121926

145 LAND GRANT, St. Augustine, Florida 32092

24Picture(s)

0Sqft

Medical / Professional Office Condo for Lease located at 145 Land Grant Street, Suite 5, St. Augustine, FL in the World Golf Village Professional Center. This brand new office suite features reception and 5 large private offices is ideal for medical, executive office, law firm, CPA, or other professional users seeking a prestigious St. Johns County business address.

$2,600

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700 ZEAGLER, Palatka, Florida 32177 MLS 2072741

700 ZEAGLER, Palatka, Florida 32177

9Picture(s)

1,690Sqft

Medical office space for lease. Located across the street from HCA Florida Putnam Hospital. Space available features a receptionist area, 5 exam rooms, 2 bathrooms, and physician's office. Improvements can be made for TI depending on length of lease. Tenant to pay $225.00 per month for water, sewer and trash.

$2,514

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1417 LARUE, Jacksonville, Florida 32207 MLS 2126476

1417 LARUE, Jacksonville, Florida 32207

29Picture(s)

1,381Sqft

This commercial property has a prime location tucked away from the busy street. One block away from San Marco shopping district. Historically 100% occupied. Upgrades include new roof, new HVAC, new plumbing and new electric both in and out. Structure is well insulated. Huge addition added to back of building. Excellent investment opportunity in San Marco.

$2,500

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2150 PARK, Jacksonville, Florida 32204 MLS 2123440

2150 PARK, Jacksonville, Florida 32204

16Picture(s)

1,421Sqft

First floor offered CRO. Just renovated! 2nd floor is separate leased residential available on 03/01/2026. Common front entrance door and foyer. Will only accept business that doesn't conflict with residents. Building, including first floor has updated electrical, plumbing and HVAC.

$2,500

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1543 KINGSLEY, Orange Park, Florida 32073 MLS 2111008

1543 KINGSLEY, Orange Park, Florida 32073

5Picture(s)

1Sqft

Formerly used as a dental office. Great location. Plenty of parking space. Water, sewer and dumpster included.

$2,500

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13453 MAIN, Jacksonville, Florida 32218 MLS 2106596

13453 MAIN, Jacksonville, Florida 32218

8Picture(s)

1,250Sqft

*Prime Office Space for Rent on N. Main Street* RENT: $2500– Negotiable This stylish office condo unit with 6 good size rooms within is perfectly situated on N. Main Street, offering a professional and convenient workspace. Ideal for businesses looking to establish a strong presence in the heart of the city. Close to River City shopping complex.

$2,500

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6100 GREENLAND, Jacksonville, Florida 32258 MLS 2109311

6100 GREENLAND, Jacksonville, Florida 32258

19Picture(s)

1,140Sqft

Prime end-unit office condo in the heart of Mandarin—ready for your business. With excellent visibility from Greenland Road and plenty of parking, this space makes a lasting impression on clients and employees alike. The inviting reception boasts 11.5-foot tray ceilings, elegant trim, and crown moldings.

$2,399

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🌴 Why Invest in Northeast Florida Commercial Real Estate

1. Strategic Location & Infrastructure
Northeast Florida sits at the crossroads of I-95, I-10, and major ports, making it ideal for logistics, retail, and industrial operations. Businesses benefit from proximity to Jacksonville International Airport, JAXPORT, and rail connections.

2. Population & Economic Growth
With rapid expansion in communities like Nocatee, Middleburg, Lake Asbury, and Green Cove Springs, local demand for retail, office, and service-based properties continues to climb.

3. Affordable Entry Point
Compared to South Florida and Central Florida markets, commercial land and buildings in Northeast Florida remain competitively priced, giving investors stronger ROI potential.

4. Diverse Property Types
Find everything from turnkey office complexes and retail plazas to vacant commercial land ready for development.

🔍 Search Commercial Properties for Sale in Northeast Florida

Use the interactive MLS search tool above to browse current commercial listings across Jacksonville, Orange Park, Green Cove Springs, Lake Asbury, Starke, Ponte Vedra, and surrounding areas.

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💼 Work with a Local Commercial Real Estate Expert

Mike Schwiebert, REALTOR® | 904HomeStore.com

As a licensed REALTOR®, former builder, and North Florida resident, Mike brings a unique perspective to commercial real estate. He understands zoning, site development, and investment analysis — helping you make informed decisions and negotiate the best deal.

Whether you’re:

• Buying land to build a new facility

• Selling an existing business property

• Expanding your investment portfolio

…Mike provides local expertise and a hands-on approach that helps clients get more value in every transaction.

📍 Serving Jacksonville, Clay County, St. Johns County, Bradford County, and all of Northeast Florida.
📞 Call or text Mike Schwiebert for a personalized consultation.