🏢 Commercial Property For Sale In Northeast Florida

Grow your business or expand your investment portfolio in one of Florida’s fastest-growing regions.

If you’re searching for commercial real estate in Northeast Florida, you’re in the right place. Whether you need retail space, office buildings, warehouses, or land for future development, Northeast Florida offers a wide range of opportunities for both investors and business owners.

From the bustling corridors of Jacksonville to the emerging growth areas of Clay County, St. Johns County, and Bradford County, this region combines a strong economy, expanding population, and business-friendly environment — making it one of Florida’s top destinations for commercial investment. See more details below.

 

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0 CONFIDENTIAL, Orange Park, Florida 32065 MLS 2117577

0 CONFIDENTIAL, Orange Park, Florida 32065

21Picture(s)

2,867Sqft

This property currently operates as a highly rated Italian restaurant and includes both real estate and business in the sale. It has been fully remodeled, has a full kitchen, amazing visibility, prime location for future Clay county development plans, and near the College. Outside has an option for future outdoor dining, and has two coolers plus a storage unit in back.

$1,200,000

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608 14TH, Fernandina Beach, Florida 32034 MLS 2081304

608 14TH, Fernandina Beach, Florida 32034

9Picture(s)

4,880Sqft

This property is zoned commercial C-1. A rare opportunity to purchase almost an acre located in the City Limits of Fernandina Beach in a very desirable location between the Amelia Island Historic District and the beach with an easy walk to parks, shopping and dining. Currently used a 5 rental spaces, fully occupied with a yearly gross income over $73,000.

$1,200,000

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2557 CHAFFEE, Jacksonville, Florida 32221 MLS 2068046

2557 CHAFFEE, Jacksonville, Florida 32221

27Picture(s)

1,976Sqft

Amazing opportunity on this mostly cleared, 1.91 acre property with greater possibilities. Property also comes with a fully renovated manufactured home. Currently zoned RMD-A. Near I-295 and I-10. Publix shopping center, Amazon, Wayfair, etc all nearby. Retention pond in the back of the property. Electrical, water, and sewage onsite.

$1,200,000

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3938 SUNBEAM, Jacksonville, Florida 32257 MLS 2090253

3938 SUNBEAM, Jacksonville, Florida 32257

28Picture(s)

4,550Sqft

Gorgeous brick office structure offering commercial and office spaces is available for sale as a superb investment and owner-user opportunity. Each unit is equipped with its own restroom and kitchen space. The property is conveniently situated to meet all tenants' necessities in San Jose. Ideal for a variety of small businesses.

$1,199,999

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2570 US HIGHWAY 1, St. Augustine, Florida 32086 MLS 2003980

2570 US HIGHWAY 1, St. Augustine, Florida 32086

12Picture(s)

3,920Sqft

Investment opportunity!! 100 feet of frontage on US 1 S in a prime location. 4 opportunities on one .56 acre lot. A residential home that is currently rented yearly (May renewal), a beauty shop with 8 booth rentals, a gun shop that is currently leased, and a separate oversized garage that can be rented as well. Walmart is situated across the street and Auto Zone is next door.

$1,100,000

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6905 OLD WOLF BAY, Palatka, Florida 32177 MLS 2120057

6905 OLD WOLF BAY, Palatka, Florida 32177

38Picture(s)

6,420Sqft

Prime medical office space in a premier location! Currently used as Putnam Diagnostic Imaging Center, this 6,420 sq ft building is located in a well-established medical district, just SW of HCA Florida Putnam Hospital.

$1,100,000

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1201 MADISON, Palatka, Florida 32177 MLS 2100508

1201 MADISON, Palatka, Florida 32177

23Picture(s)

12,983Sqft

For sale a well established Grocery store & Meat market Business and real property including 3 bedrooms 2 bathrooms apartment upstairs with approximately 5000 sq/ft vacant space that could be leased for different other businesses. Huge potential to add food restaurant as the location equipped with kitchen. **** possibility of owner financing with terms agreeable to the seller.

$1,100,000

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1503 OAK, Jacksonville, Florida 32204 MLS 2096449

1503 OAK, Jacksonville, Florida 32204

50Picture(s)

2,694Sqft

Exceptional 2,694 SF established medical office building located in the heart of Riverside's bustling 5-Points district. This turnkey opportunity features proven commercial use with flexible zoning, making it ideal for healthcare practitioners or professional services.

$1,100,000

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531 UNION, Jacksonville, Florida 32202 MLS 2102615

531 UNION, Jacksonville, Florida 32202

4Picture(s)

1,050Sqft

Welcome to UNION AND BROAD! The subject property is located at 531 W. Union Street Jacksonville, FL 32202. The base area is 1050 sq/ft and the total effective area is 1138 sq/ft. Renovated in 2017, this property has three offices, one bathroom, conference room and a flexible kitchen lounge with approx.10 parking spaces available.

$1,095,000

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481 HIGHWAY 17, Palatka, Florida 32177 MLS 2007477

481 HIGHWAY 17, Palatka, Florida 32177

32Picture(s)

17,834Sqft

Opportunity of the Century! This 9.29 Acre parcel is Zoned IL (Light Industrial) and is presently being used as Commercial Retail space through the use of a Special Use Permit.

$1,090,000

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1887 MAYPORT, Atlantic Beach, Florida 32233 MLS 2126039

1887 MAYPORT, Atlantic Beach, Florida 32233

50Picture(s)

1,574Sqft

Discover a unique building in a prime commercial location on Mayport Road, in Atlantic Beach. This concrete block structure features an appealing brick exterior and boasts an inviting open floor plan, ideal for flexible workspace configurations. As you enter, you'll appreciate the convenient handicap ramp, ensuring accessibility for all.

$1,050,000

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514 CHAFFEE POINT, Jacksonville, Florida 32221 MLS 2125410

514 CHAFFEE POINT, Jacksonville, Florida 32221

2Picture(s)

7,892Sqft

6

$1,050,000

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🌴 Why Invest in Northeast Florida Commercial Real Estate

1. Strategic Location & Infrastructure
Northeast Florida sits at the crossroads of I-95, I-10, and major ports, making it ideal for logistics, retail, and industrial operations. Businesses benefit from proximity to Jacksonville International Airport, JAXPORT, and rail connections.

2. Population & Economic Growth
With rapid expansion in communities like Nocatee, Middleburg, Lake Asbury, and Green Cove Springs, local demand for retail, office, and service-based properties continues to climb.

3. Affordable Entry Point
Compared to South Florida and Central Florida markets, commercial land and buildings in Northeast Florida remain competitively priced, giving investors stronger ROI potential.

4. Diverse Property Types
Find everything from turnkey office complexes and retail plazas to vacant commercial land ready for development.

🔍 Search Commercial Properties for Sale in Northeast Florida

Use the interactive MLS search tool above to browse current commercial listings across Jacksonville, Orange Park, Green Cove Springs, Lake Asbury, Starke, Ponte Vedra, and surrounding areas.

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💼 Work with a Local Commercial Real Estate Expert

Mike Schwiebert, REALTOR® | 904HomeStore.com

As a licensed REALTOR®, former builder, and North Florida resident, Mike brings a unique perspective to commercial real estate. He understands zoning, site development, and investment analysis — helping you make informed decisions and negotiate the best deal.

Whether you’re:

• Buying land to build a new facility

• Selling an existing business property

• Expanding your investment portfolio

…Mike provides local expertise and a hands-on approach that helps clients get more value in every transaction.

📍 Serving Jacksonville, Clay County, St. Johns County, Bradford County, and all of Northeast Florida.
📞 Call or text Mike Schwiebert for a personalized consultation.