🏢 Commercial Property For Sale In Northeast Florida

Grow your business or expand your investment portfolio in one of Florida’s fastest-growing regions.

If you’re searching for commercial real estate in Northeast Florida, you’re in the right place. Whether you need retail space, office buildings, warehouses, or land for future development, Northeast Florida offers a wide range of opportunities for both investors and business owners.

From the bustling corridors of Jacksonville to the emerging growth areas of Clay County, St. Johns County, and Bradford County, this region combines a strong economy, expanding population, and business-friendly environment — making it one of Florida’s top destinations for commercial investment. See more details below.

 

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1354 LAURA, Jacksonville, Florida 32206 MLS 2095796

1354 LAURA, Jacksonville, Florida 32206

11Picture(s)

9,000Sqft

Property features two conference rooms and a large meeting room, fully equipped kitchen and ADA-compliant bathrooms, spacious open work area for collaborative projects, individual offices all featuring built-in shelving. Prime location in the heart of the Historic Springfield District.

$1,850,000

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1828 FOSTER, Jacksonville, Florida 32216 MLS 2120442

1828 FOSTER, Jacksonville, Florida 32216

26Picture(s)

6,660Sqft

Great commercial property on .5 acres for warehousing, trucking, construction, retail, auto/sales and repair and any other business opportunities. Property has 2200 square feet of office space as well as 4400 square feet of warehouse space including 2 storage sheds.

$1,800,000

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930 UNIVERSITY, Jacksonville, Florida 32211 MLS 1140931

930 UNIVERSITY, Jacksonville, Florida 32211

26Picture(s)

6,628Sqft

BUILDING BEING SOLD AS-IS. CORNER LOCATION, COMMERCIAL NEIGHBORHOOD ZONING, 1.65 ACRES! NEW WINN DIXIE GROCERY STORE AROSS THE STREET!! Minutes from the Mathews Bridge to Downtown Jacksonville. Perfect for a retail shopping strip with national-brand tenants at a high visibility corner. Commercial Neighborhood (CN) zoning has a wide range of uses and permitted uses by exception.

$1,800,000

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5804 BEACH, Jacksonville, Florida 32207 MLS 2112200

5804 BEACH, Jacksonville, Florida 32207

8Picture(s)

12,000Sqft

This well-maintained commercial property offers approximately 12,000 square feet of income-producing space with two established tenants. The main unit, a beauty supply shop, encompasses about 10,000 to 10,500 square feet and is leased at $8,225 per month including sales tax, with a 3% annual rent increase in place.

$1,800,000

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5464 GEORGE HODGES, Macclenny, Florida 32063 MLS 2015183

5464 GEORGE HODGES, Macclenny, Florida 32063

23Picture(s)

2,096Sqft

Amazing commercial land opportunity! Land is substantially cleared and can be easily hooked up to city water and sewer which runs through this site already! Excellent view from I-10 along south side of site with approx. 1075' of interstate 10 road frontage! This property would be perfect for many ideas including multifamily townhomes/apartments, car dealerships etc…

$1,700,000

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4310 BARKOSKIE, Jacksonville, Florida 32258 MLS 2098223

4310 BARKOSKIE, Jacksonville, Florida 32258

31Picture(s)

6,206Sqft

Prime opportunity to purchase a 6,206 SF standalone building situated on a spacious 0.84-acre lot along high-traffic Old St. Augustine Road. This turn-key facility is ideal for schools, daycare centers, medical offices, or professional office use, offering flexible PUD zoning to accommodate a wide range of business types, including retail.

$1,695,000

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2758 US HIGHWAY 1, St. Augustine, Florida 32086 MLS 2103280

2758 US HIGHWAY 1, St. Augustine, Florida 32086

6Picture(s)

2,474Sqft

Commercial Building for Sale in St Augustine previously used as a medical office.

$1,690,000

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6 ST JOHNS MEDICAL PARK, St. Augustine, Florida 32086 MLS 2122701

6 ST JOHNS MEDICAL PARK, St. Augustine, Florida 32086

79Picture(s)

4,028Sqft

Occupancy available April 2026. Unique opportunity to move your busy practice into the entire building or convert back to Suite A and B, lease the additional space and share building expenses. The building was originally constructed with separate electric and water meters, separate entrances and offices.

$1,550,000

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222 SAN MARCO, St. Augustine, Florida 32084 MLS 2116538

222 SAN MARCO, St. Augustine, Florida 32084

1Picture(s)

3,540Sqft

This 4,116 sq. ft. office building features 120 feet of frontage along San Marco/A1A and includes a covered patio. The property offers 3,540 sq. ft. of heated and cooled space, currently divided into three office suites, each with private entrances. With 17 on-site parking spaces, this property presents endless opportunities for establishing your own business in the heart of downtown St.

$1,500,000

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5646-C STATE ROAD 16, St. Augustine, Florida 32092 MLS 2112021

5646-C STATE ROAD 16, St. Augustine, Florida 32092

11Picture(s)

3,286Sqft

DEVELOPMENT OPPORTUNITY! WORLD GOLF VILLAGE CORRIDER!!! Package total of 6.61 ACRES WITH 280 FEET OF ROAD FRONTAGE DIRECTLY ON HEAVILY TRAVELLED STATE ROAD 16 . This particular parcel is 1.97 Acres being sold as a package with the adjacent 4.94 Acres. Currently zoned multifamily, the parcel contains multiple buildings including a 4/2.5 Single Family residence, and a 2/2 doublewide Mobile Home .

$1,500,000

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755 HIGHWAY 17, San Mateo, Florida 32187 MLS 2106325

755 HIGHWAY 17, San Mateo, Florida 32187

24Picture(s)

3,975Sqft

Strategically positioned at the high-traffic intersection of US Highway 17 and Horse Landing Road, this Commercial/R-2 property presents a compelling opportunity for developers and investors alike.

$1,500,000

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711 CASSAT, Jacksonville, Florida 32205 MLS 2105205

711 CASSAT, Jacksonville, Florida 32205

4Picture(s)

6,909Sqft

711 Cassat Avenue, located in Jacksonville, Florida, offers a vibrant and convenient location for various uses. This property features a spacious layout with ample square footage, providing flexibility for retail, office or industrial use purposes.

$1,500,000

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🌴 Why Invest in Northeast Florida Commercial Real Estate

1. Strategic Location & Infrastructure
Northeast Florida sits at the crossroads of I-95, I-10, and major ports, making it ideal for logistics, retail, and industrial operations. Businesses benefit from proximity to Jacksonville International Airport, JAXPORT, and rail connections.

2. Population & Economic Growth
With rapid expansion in communities like Nocatee, Middleburg, Lake Asbury, and Green Cove Springs, local demand for retail, office, and service-based properties continues to climb.

3. Affordable Entry Point
Compared to South Florida and Central Florida markets, commercial land and buildings in Northeast Florida remain competitively priced, giving investors stronger ROI potential.

4. Diverse Property Types
Find everything from turnkey office complexes and retail plazas to vacant commercial land ready for development.

🔍 Search Commercial Properties for Sale in Northeast Florida

Use the interactive MLS search tool above to browse current commercial listings across Jacksonville, Orange Park, Green Cove Springs, Lake Asbury, Starke, Ponte Vedra, and surrounding areas.

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💼 Work with a Local Commercial Real Estate Expert

Mike Schwiebert, REALTOR® | 904HomeStore.com

As a licensed REALTOR®, former builder, and North Florida resident, Mike brings a unique perspective to commercial real estate. He understands zoning, site development, and investment analysis — helping you make informed decisions and negotiate the best deal.

Whether you’re:

• Buying land to build a new facility

• Selling an existing business property

• Expanding your investment portfolio

…Mike provides local expertise and a hands-on approach that helps clients get more value in every transaction.

📍 Serving Jacksonville, Clay County, St. Johns County, Bradford County, and all of Northeast Florida.
📞 Call or text Mike Schwiebert for a personalized consultation.