Commercial Property for Sale In North East Florida Jacksonville - Orange Park - St Augustine - Middleburg - Beaches

🏢 Commercial Property For Sale In Northeast Florida

Grow your business or expand your investment portfolio in one of Florida’s fastest-growing regions.

If you’re searching for commercial real estate in Northeast Florida, you’re in the right place. Whether you need retail space, office buildings, warehouses, or land for future development, Northeast Florida offers a wide range of opportunities for both investors and business owners.

From the bustling corridors of Jacksonville to the emerging growth areas of Clay County, St. Johns County, and Bradford County, this region combines a strong economy, expanding population, and business-friendly environment — making it one of Florida’s top destinations for commercial investment. See more details below.

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30 BARBER, Macclenny, Florida 32063 MLS 2108124

30 BARBER, Macclenny, Florida 32063

43Picture(s)
6,544Sqft
Available now: 6,544 sq ft industrial warehouse in a prime Macclenny, FL location just off the main road. Zoned for industrial use, this versatile space features 3-phase power, two HVAC units, and an open-air floor plan ideal for manufacturing, distribution, or storage. The building includes a separate office and private restroom, providing a functional workspace for operations.
$5,453

12276 SAN JOSE, Jacksonville, Florida 32223 MLS 2065326

12276 SAN JOSE, Jacksonville, Florida 32223

13Picture(s)
2,706Sqft
Jaxoffices Professional Business Park Located in the South Mandarin market of Jacksonville. Jaxoffices Professional Business Park, consists of a 7 Building Class ''A'' Professional Medical and Office Park with Call Centers, Financial, Insurance, Real Estate and 4 Family Medical Practices, 2 Allergists, Audiologists, Podiatrist, Dental and more.
$5,015

167 COMFORT, Palatka, Florida 32177 MLS 2084264

167 COMFORT, Palatka, Florida 32177

29Picture(s)
9,050Sqft
Exceptional Commercial/Flex Space Opportunity in Palatka's Growing Port District Unlock the potential for your business with this expansive 9,050 sq. ft. commercial/flex space NNN Lease situated on a substantial 3.19-acre lot.
$5,000

8282 WESTERN WAY, Jacksonville, Florida 32256 MLS 2082835

8282 WESTERN WAY, Jacksonville, Florida 32256

1Picture(s)
53,424Sqft
8282 Western Way Cir, provides turn-key newly built out office space. This is ideal for a wide range of professional office. The landlord if offering custom build-out, providing a rare opportunity to design a new construction interior. Subject property provides ADA complaint restrooms already in place, elevators, 24/7 access, onsite fenced parking spaces, and more.
$4,840

559 TWINCOURT, St. Augustine, Florida 32095 MLS 2118339

559 TWINCOURT, St. Augustine, Florida 32095

3Picture(s)
0Sqft
Office space for lease in World Golf Village, available December or January with 30 days' notice. Please schedule appointments in advance. The current layout includes two private offices, a kitchen, a private bath, and a conference room. Ideal for a medical practice or professional office.
$4,458

2219 COUNTY ROAD 220, Middleburg, Florida 32068 MLS 2116146

2219 COUNTY ROAD 220, Middleburg, Florida 32068

6Picture(s)
1,474Sqft
Excellent opportunity to lease a retail/office condo in Middleburg close to Fleming Island. This space offers 1,474 +/- SF available within The Silo Shoppes of Heritage Farm. This space has recently been upgraded with a new restroom, HVAC, and electric. The property is within an established association with monthly dues around $339 per month.
$4,219

1334 WALNUT, Jacksonville, Florida 32206 MLS 2082168

1334 WALNUT, Jacksonville, Florida 32206

27Picture(s)
3,500Sqft
A spacious and functional office suite at 1334 Walnut Street, offering approximately 2,333 square feet of well-designed professional space. This is the larger of two suites in a 3,500 square foot building, located on a quiet street that provides both convenience and a calm working environment.
$4,163

4613 PHILIPS, Jacksonville, Florida 32207 MLS 2069564

4613 PHILIPS, Jacksonville, Florida 32207

10Picture(s)
43,076Sqft
Prime Office Space for Lease. Discover an exceptional office space opportunity in a well-maintained building, offering modern amenities and a strategic location. This lease includes access to common area restrooms, ensuring convenience for tenants. Additionally, the building is fiber-ready, providing high-speed connectivity to support your business operations seamlessly.
$4,033

415 PONCE DE LEON, St. Augustine, Florida 32084 MLS 2114199

415 PONCE DE LEON, St. Augustine, Florida 32084

8Picture(s)
1,335Sqft
Building was originally a restaurant for many years. Most recently occupied as a retail fish/seafood Market that recently closed. Area available also includes the area previously occupied as a retail fruit stand. Hood vent still in place. Area not measured Lots of possibilities. Large majestic trees, could create a great ambiance for outdoor dining.
$4,000

11555 CENTRAL, Jacksonville, Florida 32224 MLS 2104515

11555 CENTRAL, Jacksonville, Florida 32224

5Picture(s)
2,310Sqft
Very convenient location near i-295 corridor. Close to towncenter, UNF, beaches and southside. The office of east park hosts mostly doctors, accountants, insurance, law offices, chiropractors and more! Highly professional office park with little turnover. This double unit office has 9 offices, reception office, 2 ADU compliant bathrooms and a kitchen/breakroom.
$4,000

2960 STRICKLAND, Jacksonville, Florida 32254 MLS 2097523

2960 STRICKLAND, Jacksonville, Florida 32254

10Picture(s)
4,050Sqft
This 4,050SF office building with Industrial Light zoning is located in the heart of Jacksonville; just three miles from downtown,16 miles from the Jacksonville International Airport, and 13 miles to JAXPORT.
$3,663

4549 ST AUGUSTINE, Jacksonville, Florida 32207 MLS 2099148

4549 ST AUGUSTINE, Jacksonville, Florida 32207

7Picture(s)
75,595Sqft
This multi-tenant industrial park offers three (3) units spanning from 1,500 +/- SF to 3,000 +/- SF in Jacksonville's highly desired Southside sub-market. Each unit consists of a quality office, restroom, and functional warehouse, along with its own dedicated grade-level drive- in door (approximately 12' wide 12' high) for convenient access and operational efficiency. Excellent location on St.
$3,625
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🌴 Why Invest in Northeast Florida Commercial Real Estate

1. Strategic Location & Infrastructure
Northeast Florida sits at the crossroads of I-95, I-10, and major ports, making it ideal for logistics, retail, and industrial operations. Businesses benefit from proximity to Jacksonville International Airport, JAXPORT, and rail connections.

2. Population & Economic Growth
With rapid expansion in communities like Nocatee, Middleburg, Lake Asbury, and Green Cove Springs, local demand for retail, office, and service-based properties continues to climb.

3. Affordable Entry Point
Compared to South Florida and Central Florida markets, commercial land and buildings in Northeast Florida remain competitively priced, giving investors stronger ROI potential.

4. Diverse Property Types
Find everything from turnkey office complexes and retail plazas to vacant commercial land ready for development.

🔍 Search Commercial Properties for Sale in Northeast Florida

Use the interactive MLS search tool above to browse current commercial listings across Jacksonville, Orange Park, Green Cove Springs, Lake Asbury, Starke, Ponte Vedra, and surrounding areas.

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💼 Work with a Local Commercial Real Estate Expert

Mike Schwiebert, REALTOR® | 904HomeStore.com

As a licensed REALTOR®, former builder, and North Florida resident, Mike brings a unique perspective to commercial real estate. He understands zoning, site development, and investment analysis — helping you make informed decisions and negotiate the best deal.

Whether you’re:

  • Buying land to build a new facility

  • Selling an existing business property

  • Expanding your investment portfolio

…Mike provides local expertise and a hands-on approach that helps clients get more value in every transaction.

📍 Serving Jacksonville, Clay County, St. Johns County, Bradford County, and all of Northeast Florida.
📞 Call or text Mike Schwiebert for a personalized consultation.

Mike

See Come Vacant Lots – land for sale here HERE
If you are looking to buy or sell a home on Black Creek you have come to the right place. I would love to help you find your next home. When you see something you like please call, text, or email me anytime and I will get to work for you. Call Mike Schwiebert Realtor at 904-562-9345. Voted Best Real Estate Agent 2019 in Clay County!

Mike Schwiebert Best Realtor In Clay County